Ken Ikeda Selected Research

Cyclosporine (Ciclosporin)

3/2007	Amelioration of collagen-induced arthritis in mice by a novel phosphodiesterase 7 and 4 dual inhibitor, YM-393059.
11/2006	Pharmacological profile of a novel phosphodiesterase 7A and -4 dual inhibitor, YM-393059, on acute and chronic inflammation models.

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Ken Ikeda Research Topics

Disease

12	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 07/2002
10	Parkinson Disease (Parkinson's Disease) 06/2019 - 01/2002
6	Motor Neuron Disease (Primary Lateral Sclerosis) 07/2015 - 03/2002
5	Migraine Disorders (Migraine) 04/2018 - 09/2006
5	Overactive Urinary Bladder (Overactive Bladder) 12/2006 - 08/2002
4	Dyskinesias (Dyskinesia) 01/2018 - 01/2002
4	Muscle Weakness 07/2015 - 09/2002
3	Parkinsonian Disorders (Parkinsonism) 06/2019 - 12/2004
3	Atrophy 01/2015 - 10/2009
3	Alzheimer Disease (Alzheimer's Disease) 01/2014 - 01/2013
3	Disease Progression 01/2013 - 01/2011
3	Facial Nerve Injuries 02/2011 - 06/2003
2	Neoplasms (Cancer) 07/2020 - 11/2009
2	Headache (Headaches) 05/2017 - 01/2009
2	Dyslipidemias (Dyslipidemia) 03/2017 - 01/2011
2	Epilepsy (Aura) 03/2017 - 01/2011
2	Cerebral Infarction 03/2017 - 01/2015
2	Contracture 07/2015 - 01/2015
2	Ischemic Stroke 12/2012 - 01/2008
2	Diabetes Mellitus 01/2011 - 09/2002
2	Stroke (Strokes) 01/2011 - 01/2008
2	Pruritus (Itching) 11/2010 - 04/2008
2	Schizophrenia (Dementia Praecox) 11/2010 - 03/2009
2	Hypertension (High Blood Pressure) 07/2010 - 05/2010
1	Severe Acute Respiratory Syndrome 01/2022
1	Communicable Diseases (Infectious Diseases) 01/2022
1	Biliary Tract Neoplasms (Biliary Tract Cancer) 07/2020
1	Essential Tremor (Essential Tremors) 06/2019
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 03/2017
1	Abdominal Pain (Pain, Abdominal) 01/2017
1	Pathologic Constriction (Stenosis) 01/2017
1	Colonic Neoplasms (Colon Cancer) 01/2017
1	Cerebrotendinous Xanthomatosis 02/2016
1	Dementia (Dementias) 10/2014
1	Carbon Monoxide Poisoning (Poisoning, Carbon Monoxide) 03/2014
1	Poisoning 03/2014
1	Dystonia (Limb Dystonia) 01/2014

Drug/Important Bio-Agent (IBA)

4	Pharmaceutical PreparationsIBA 06/2019 - 08/2002
4	LipidsIBA 03/2017 - 01/2011
4	TRK 820IBA 11/2010 - 04/2008
4	kappa Opioid Receptors (kappa Opioid Receptor)IBA 11/2010 - 04/2008
4	T 588IBA 07/2007 - 03/2002
4	Solifenacin Succinate FDA Link 12/2006 - 08/2002
4	oxybutynin (Tavor)FDA LinkGeneric 10/2005 - 08/2002
3	mecobalamin (methylcobalamin)IBA 01/2022 - 07/2015
3	lomerizineIBA 04/2018 - 01/2011
3	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 04/2018 - 01/2011
3	Methylprednisolone FDA LinkGeneric 03/2014 - 01/2011
3	Levodopa (L Dopa)FDA LinkGeneric 01/2013 - 08/2008
3	AntibodiesIBA 01/2013 - 11/2010
3	olmesartanIBA 05/2010 - 07/2002
3	N- (4,6- dimethylpyrimidin- 2- yl)- 4- (2- (4- methoxy- 3- methylphenyl)- 5- (4- methylpiperazin- 1- yl)- 4,5,6,7- tetrahydro- 1H- indol- 1- yl)benzenesulfonamide difumarateIBA 03/2007 - 07/2006
3	Muscarinic AntagonistsIBA 05/2004 - 08/2002
2	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 06/2019 - 01/2018
2	Selegiline (E250)FDA LinkGeneric 01/2018 - 01/2013
2	Dopamine Agonists (Dopamine Agonist)IBA 01/2018 - 01/2016
2	Angiotensin Receptor AntagonistsIBA 05/2017 - 05/2010
2	SteroidsIBA 01/2017 - 01/2011
2	Neuroprotective AgentsIBA 07/2015 - 01/2002
2	Memantine (Namenda)FDA Link 03/2014 - 01/2013
2	Donepezil (Aricept)FDA LinkGeneric 01/2014 - 01/2013
2	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2014 - 01/2013
2	IronIBA 09/2013 - 01/2012
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2013 - 01/2013
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2012 - 01/2011
2	Uric Acid (Urate)IBA 01/2012 - 01/2011
2	Ferritins (Ferritin)IBA 01/2012 - 01/2011
2	Prednisolone (Predate)FDA LinkGeneric 01/2011 - 01/2011
2	Immunoglobulin G (IgG)IBA 01/2011 - 11/2010
2	AntipruriticsIBA 11/2010 - 04/2008
2	Superoxide Dismutase-1IBA 01/2010 - 10/2005
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 03/2007 - 11/2006
2	darifenacin FDA Link 05/2004 - 01/2004
2	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 05/2004 - 01/2004
2	Tolterodine Tartrate (Detrol)FDA Link 05/2004 - 01/2004
1	VaccinesIBA 01/2022
1	Monoclonal AntibodiesIBA 01/2022
1	Zonisamide (Zonegran)FDA LinkGeneric 01/2018
1	entacapone (Comtan)FDA Link 01/2018
1	Telmisartan (Micardis)FDA Link 05/2017
1	Tryptamines (Triptans)IBA 05/2017
1	Analgesics (Analgesic Drugs)IBA 05/2017
1	Anticonvulsants (Antiepileptic Drugs)IBA 03/2017
1	SterolsIBA 02/2016
1	Cholestanetriol 26-Monooxygenase (Cholestanetriol 26 Monooxygenase)IBA 02/2016
1	rotigotine FDA Link 01/2016
1	EdaravoneIBA 01/2015
1	Free Radical ScavengersIBA 01/2015
1	Amyloid (Amyloid Fibrils)IBA 10/2014
1	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2014

Therapy/Procedure

12	Therapeutics 07/2020 - 01/2002
3	Denervation 01/2015 - 10/2009
3	Oral Administration 01/2011 - 06/2003
3	Drug Therapy (Chemotherapy) 11/2009 - 08/2002
2	Renal Dialysis (Hemodialysis) 11/2010 - 04/2008
1	Tracheostomy 01/2022
1	Decompression 01/2017
1	Colectomy 01/2017
1	Transdermal Patch 01/2016
1	Hyperbaric Oxygenation 03/2014